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Britain to sign cancer treatments deal with Germany’s BioNTech

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Research into new cancer treatments could be sped up by a government deal with a leading pharmaceutical company, British Health Secretary Steve Barclay has said.

Barclay is due to sign a memorandum of understanding with Germany’s BioNTech on Friday, to “ensure the best possible treatments are available as soon as possible” for cancer.

The agreement means cancer patients in England will get early access to trials exploring personalised messenger ribonucleic acid (mRNA) therapies, like cancer vaccines, possibly from as early as autumn this year.

BioNTech worked with Pfizer to develop the widely-used mRNA vaccination against COVID-19, and its partnership with the British government could deliver 10,000 doses of personalised therapies to British patients by 2030 through a new research and development hub.

Barclay said: “Once cancer is detected, we need to ensure the best possible treatments are available as soon as possible, including for breast, lung, and pancreatic cancer.

“BioNTech helped lead the world on a COVID-19 vaccine and they share our commitment to scientific advancement, innovation and cutting-edge scientific technology, making them perfect partners for a deal to work together on cancer vaccines.”

He added: “This partnership will mean that, from as early as September, our patients will be among the first to participate in trials and tests to provide targeted, personalised, and precision treatments using transformative new therapies to both treat the existing cancer and help stop it returning.

“This agreement builds on this government’s promise to increase research and development spending to £20 billion ($23.8 billion) per year and demonstrates the UK remains one of the most attractive places in the world for innovative companies to invest in research, trial new treatments and treat patients more effectively.”

Prof. Uğur Şahin, chief executive and co-founder of BioNTech said: “The UK successfully delivered COVID-19 vaccines so quickly because the National Health Service, academia, the regulator and the private sector worked together in an exemplary way.

“This agreement is a result of the lessons learnt from the COVID-19 pandemic.

“Drug development can be accelerated without cutting corners if everyone works seamlessly together towards the same goal.

“Today’s agreement shows we are committed to do the same for cancer patients.”

Şahin added: “Our goal is to accelerate the development of immunotherapies and vaccines using technologies we have been researching for over 20 years.

The collaboration will cover various cancer types and infectious diseases affecting collectively hundreds of millions of people worldwide.

“If successful, this collaboration has the potential to improve outcomes for patients and provide early access to our suite of cancer immunotherapies as well as to innovative vaccines against infectious diseases – in the UK and worldwide.”

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Nigeria records progress in HIV/AIDS response- Minister

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The Federal Government says Nigeria has made huge progress in the HIV/AIDS response and is on the way to ending the disease by 2030.

The Minister of State for Health, Dr Tunji Alausa, disclosed this on Thursday during a media conference to mark the 2023 World AIDS Day.

The theme of the 2023 commemoration is “Let Communities Lead”.

Alausa also unveiled some National HIV/AIDS, Viral Hepatitis and Sexually Transmitted Infections (STIs) policy documents which are meant to strengthen the existing framework for action, in order to reduce the spread of the diseases and manage their impact.

The Documents are National Guidelines for Viral Hepatitis Treatment and Care – 2023, Information, Education and Communication (IEC) materials for Prevention of Mother-To-Child Transmission (PMTCT) demand creation and scale-up-2023.

Others are Standard Operating Procedures (SOPs) for PMTCT scale up, jingles in 10 languages for PMTCT scale-up – 2023 and IEC materials for HIV self-testing scale up – 2022

According to Alausa, the laudable progress in the response to the disease was made in the last two decades towards ending the epidemic by 2030.

“Nigeria with the current HIV treatment coverage above 90 per cent is well on course to meet this goal.

“Currently, Nigeria has 1.6 million People Living with HIV/AIDS (PLHIV) on treatment out of 1.9 million.”

He added that communities contribute to the HIV/AIDS response in numerous ways as  their leadership and advocacy ensure that the response remains relevant and grounded, keeping people at the centre and leaving no one behind.

“We cannot achieve lasting progress in our battle against HIV/AIDS without the active involvement of our communities.

“Our communities and community structures are not merely recipients of care; they are champions of change, the catalysts for progress, and the backbone of our collective resilience. “

He also said that tremendous efforts that have been made by successive governments and other stakeholders to control the HIV epidemic by averting new transmission and improving lives cannot be over emphasised.

Alausa said that in November 2020, Nigeria joined a multi-country learning network “the HIV Coverage, Quality, and Impact Network (CQUIN)” under the leadership of the National AIDS and STIs Control Program.

This was with the aim of learning and sharing knowledge to support the coordination and scale- up of Differentiated Service Delivery (DSD) for HIV in Nigeria.

He added that other means of progress have been through the scaling up of numerous interventions and services.

While giving an update on the state of HIV epidemics in Nigeria, the National Coordinator National AIDS, Viral Hepatitis and STIs Control Programme (NASCP), Dr Adebobola Bashorun, said there has been steady declines in annual HIV infections and AIDS related deaths.

He however said that out of the 1.9 million PLHIV, 270,000 had not been identified and that as at 2022, 159,923 estimated children aged zero to 14 years were living with HIV in Nigeria; making it one of the countries with the highest paediatric HIV burden globally.

“Also, 20,364 HIV exposed infants (HEIs) had Early Infant Diagnosis (EID) samples collected within two months of delivery, which translates to only 21 per cent EID coverage and a MTCT rate of 14 per cent at six weeks and 23 per cent through breastfeeding.

“96,517estimated HIV positive pregnant women who needed PMTCT, only 34 per cent were enrolled on Anti-Retroviral Treatment (ART) in 2022.

“However, 50,676 children living with HIV (CLHIV) were on treatment in 2022 which represents 32  per cent of the estimated CLHIVs.”

Bashorun noted that in spite of the current efforts towards paediatric case finding and linkage to HIV treatment, many children remain undiagnosed and thus without access to life saving ART.

He added that it was critical to identify these children and initiate ART as early as possible.

On his part, the Chairman, House Committee on AIDS, Tuberculosis and Malaria Control (ATM), Hon. Amobi Ogah, said that its very important for Nigeria to recommit to reducing foreign support to at least 50 per cent.

“We are not unmindful that over 90 per cent of funding for HIV/AIDS activities through programs in our country come from foreign partners.

“I therefore call on the Federal Government to look inwards in supporting domestic funding because it is high time we decide our fate and not be dependent on foreign aid which does not do us any good.”

He, however, assured that the  legislature would work towards the increase of budgetary allocation to the fight against HIV/AIDS within the face of limited resources.

“We will also provide the legislative framework to protect the rights of people living with HIV and other forms of discrimination and stigmatisation”, he added.

The World Health Organisation (WHO), Universal Health Coverage Cluster Lead, Dr Chavan Laxmikant, said that the gains recorded should be consolidated through the creation of enabling environments for community leadership, continued adoption of innovative approaches for HIV prevention, treatment and care.

“We call on the government of Nigeria and its partners to empower the communities to take up leadership by providing an enabling environment and addressing cross-cutting issues-punitive laws and policies, stigma and discrimination, gender inequality and violence that hinder the communities.”

The World AIDS Day is commemorated on Dec. 1 every year to raisee awareness about HIV/AIDS, show support to people living with HIV and remember those people who have lost their lives to the infection. 

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Nigeria records significant decline in HIV/AIDS transmission — FG

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Dr Gambo Aliyu, the Director-General, National Agency for the Control of AIDS (NACA), says Nigeria has recorded significant decline in the number of persons infected with HIV/AIDS.

He disclosed this at a news conference in Abuja on Friday, ahead of the 2023 World AIDS Day (WAD).

The WAD is a global observance, annually celebrated on Dec. 1 around the world to raise awareness about the AIDS pandemic, caused by the spread of HIV infection and mourning those who died of the disease.

The day has “Communities: Leadership to End AIDS by 2030” as its theme for 2023.

The NACA boss, therefore, said “Nigeria like many other countries has made significant strides in the fight against HIV/AIDS, but there is still much to be done to achieve the goal of ending AIDS as a public health threat by 2030.

“Nigeria has the second largest burden of HIV infection. Currently, a total of 1.8 million persons are estimated to be living with HIV in the country, out of which, about 1.63 million are already on Antiretroviral Therapy (ART), a lifesaving medication.

“Approximately, 58 per cent are estimated to be females, and 42 per cent are males.

“The national average Mother-To-Child Transmission rate of 22 per cent is driven by a large number of states with transmission rates above 25 per cent and few states with rates below 15 per cent.

“Nigeria is responsible for about 30 per cent of the world’s gap in Prevention of Mother to Child Transmission (PMTCT).”

He said that the declining figure was achieved with the support of partners and global communities to prevent new infections, increase HIV awareness and knowledge and support those living with and affected by HIV/AIDS.

He, however, stressed the need to address social and structural factors that drive the HIV epidemic.

“It is imperative that we confront these systemic inequalities head-on and work to ensure that all individuals have equal access to life-saving prevention, treatment and care services, as well as  other social services available to Nigerians,” he said.

Dr Leo Zekeng, the Country Director of UNAIDS, who said that the UN body is committed

to continuous support to the Federal Government in eliminating HIV/AIDS, added that “we have made remarkable progress not only in Nigeria, but worldwide as about 30 million people are on treatment, which is remarkable.

“AIDS is no longer the deadly disease that it used to be, and those who are diagnosed with HIV but follow every rules and take the medication can live a normal life.”

On his part, Amobi Ogah, Chairman, House Committee on HIV/AIDS, Tuberculosis and Malaria Control (ARM), said the parliament was working toward increasing budgetary allocation to fight the disease in the country.

He said “we assure you that the National Assembly will work toward increasing budgetary allocation to the fight against HIV/AIDS in the face of limited resources.

“We will also provide the legislative framework to protect the rights of People Living with HIV and other forms of discrimination and stigmatisation.”

Mr Abdulkadir Ibrahim, the National Coordinator, Network of People Living with HIV/AIDS in Nigeria (NEPWHAN), said that the theme of the 2023 WAD recognises the need for communities to support programmes and initiatives toward achieving the 2030 target of ending AIDS.

Ibrahim, who was represented by Mr James Atusue, urged communities to tackle obstacles  standing in the way of providing HIV services to those who required them most.

He said “as a network, we continue to mobilise our community in solidarity, helping those living with HIV, and those affected by HIV to deal with stigma and discrimination, and support them to know existing services from the social and economic perspective.”

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Minister unveils policy on mental health, suicide prevention

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Co-ordinating Minister of Health and Social Welfare, Muhammad Ali Pate has unveiled the “National Mental Health Policy” and the “National Suicide Prevention Strategic Framework” in Abuja yesterday.

The Minister commended the team that worked on the policy documents noting that they had worked extensively and invested in it.

He further noted that the policy was a followup to the resolution at the #NCH64 to “Adopt and implement the National Suicide Prevention Strategic Framework in the 36 States of the Federation and FCT.”

“Good mental health, including emotional, psychological, and social well-being of every Nigerian is an essential factor in the Renewed Hope Agenda of Mr President,” he explained.

The Minister promised to implement the policies by promoting understanding of mental health conditions and increasing access to healthcare for those who need it.

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