Napoli president, Aurelio De Laurentiis says Victor Osimhen is not in a position to face AC Milan on Wednesday.
The Partenopei will travel to San Siro for the first leg of their UEFA Champions League quarter-final tie.
Osimhen picked up a muscle injury while representing Nigeria late last month.
Napoli were hoping the forward would be available to face the current Serie A champions but will have to look for another option.
“Victor is not in a position to play, unfortunately. We hope to have him back for the return fixture at the Maradona on April 18,” De Laurentiis was quoted by La Repubblica.
Osimhen has scored four goals in five appearances in the Champions League this season.